There's a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors during the dorsal horn to lessen afferent agony transmission and develop analgesia. Hence, medicine like clonidine that target alpha-two receptors can affect the transmission of pain. Clonidine is dispersed in breast milk; caution is https://aaronl369sok8.nytechwiki.com/user