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Fast administration of large-dose opioid agonists may well transiently elevate ICP and reduce cerebral perfusion pressures. These occasions are connected to opioid-induced lowering of mean arterial tension, which stimulates a regulatory response to extend cerebral blood stream resulting in greater ICP. Opioid agonist-induced respiratory depression can develop cerebral hypoxia and https://curepain.co.uk/product/mallinckrodt-morphine-sulfate-200mg/

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